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Cytokeratin 7 (KRT7) (NM_005556) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human keratin 7 (KRT7), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

CK7; K2C7; K7; SCL

Gene ID

3855

UniProt

P08729

Accession Number mRNA

NM_005556

Chromosomal Location

12q13.13

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

ES Cell Differentiation/IPS

Molecular Weight

79.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KRT7

Species

Human

Protein ID

NP_005547

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3855

Uniprot URL

https://www.uniprot.org/uniprot/P08729

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005556

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005547

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