DLX3 (NM_005220) Human Recombinant Protein
Product Specifications
Background
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]
Synonyms
AI4; TDO
Gene ID
1747
UniProt
O60479
Accession Number mRNA
NM_005220
Chromosomal Location
17q21.33
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
59.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DLX3
Species
Human
Protein ID
NP_005211
Overview
Purified recombinant protein of Human distal-less homeobox 3 (DLX3), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1747
Uniprot URL
https://www.uniprot.org/uniprot/O60479
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005220
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005211
Curated Selection
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