MCM5 (NM_006739) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human minichromosome maintenance complex component 5 (MCM5), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
CDC46; MGORS8; P1-CDC46
Gene ID
4174
UniProt
P33992, B1AHB0
Accession Number mRNA
NM_006739
Chromosomal Location
22q12.3
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Cell cycle, DNA replication
Field of Research
Cell cycle, DNA replication
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Stem cell - Pluripotency, Transcription Factors
Molecular Weight
110.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MCM5
Species
Human
Protein ID
NP_006730
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4174
Uniprot URL
https://www.uniprot.org/uniprot/P33992
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006739
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006730
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