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HOXC5 (NM_018953) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. [provided by RefSeq, Jul 2008]

Synonyms

CP11; HOX3; HOX3D

Gene ID

3222

UniProt

Q00444

Accession Number mRNA

NM_018953

Chromosomal Location

12q13.13

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Transcription Factors

Molecular Weight

24.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HOXC5

Species

Human

Protein ID

NP_061826

Overview

Purified recombinant protein of Human homeobox C5 (HOXC5), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3222

Uniprot URL

https://www.uniprot.org/uniprot/Q00444

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018953

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061826

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