C14orf172 (TRMT61A) (NM_152307) Human Recombinant Protein

Product Specifications

Background

Catalytic subunit of tRNA (adenine-N (1) -) -methyltransferase, which catalyzes the formation of N (1) -methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508) . Catalytic subunit of mRNA N (1) -methyltransferase complex, which mediates methylation of adenosine residues at the N (1) position of a small subset of mRNAs: N (1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human tRNA methyltransferase 61 homolog A (S. cerevisiae) (TRMT61A), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Synonyms

C14orf172; GCD14; Gcd14p; hTRM61; TRM61

Gene ID

115708

UniProt

Q96FX7, A0A024R6Q2

Accession Number mRNA

NM_152307

Chromosomal Location

14q32.33

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome

Molecular Weight

31.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.