CDCA5 (NM_080668) Human Recombinant Protein

Product Specifications

Background

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human cell division cycle associated 5 (CDCA5), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Synonyms

SORORIN

Gene ID

113130

UniProt

Q96FF9, A0A024R5D6

Accession Number mRNA

NM_080668

Chromosomal Location

11q13.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome

Molecular Weight

27.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.