CDCA5 (NM_080668) Human Recombinant Protein
Product Specifications
Background
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human cell division cycle associated 5 (CDCA5), full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Synonyms
SORORIN
Gene ID
113130
UniProt
Q96FF9, A0A024R5D6
Accession Number mRNA
NM_080668
Chromosomal Location
11q13.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome
Molecular Weight
27.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CDCA5
Species
Human
Protein ID
NP_542399
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/113130
Uniprot URL
https://www.uniprot.org/uniprot/Q96FF9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_080668
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_542399
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