EED (NM_152991) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human embryonic ectoderm development (EED), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
COGIS; HEED; WAIT1
Gene ID
8726
UniProt
O75530
Accession Number mRNA
NM_152991
Chromosomal Location
11q14.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
45.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EED
Species
Human
Protein ID
NP_694536
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8726
Uniprot URL
https://www.uniprot.org/uniprot/O75530
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_152991
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_694536
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