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RGS13 (NM_144766) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human regulator of G-protein signaling 13 (RGS13), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

MGC17173

Gene ID

6003

UniProt

O14921

Accession Number mRNA

NM_144766

Chromosomal Location

1q31.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Function

Druggable Genome

Molecular Weight

19 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RGS13

Species

Human

Protein ID

NP_658912

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6003

Uniprot URL

https://www.uniprot.org/uniprot/O14921

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_144766

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_658912

Frequently Asked Questions

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