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H10 (H1F0) (NM_005318) Human Recombinant Protein

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]

Overview

Purified recombinant protein of Human H1 histone family, member 0 (H1F0), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

H1.0; H1F0; H1FV; H10

Gene ID

3005

UniProt

P07305

Accession Number mRNA

NM_005318

Chromosomal Location

22q13.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome

Molecular Weight

20.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

H1-0

Species

Human

Protein ID

NP_005309

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3005

Uniprot URL

https://www.uniprot.org/uniprot/P07305

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005318

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005309

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