H10 (H1F0) (NM_005318) Human Recombinant Protein
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
Overview
Purified recombinant protein of Human H1 histone family, member 0 (H1F0), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
H1.0; H1F0; H1FV; H10
Gene ID
3005
UniProt
P07305
Accession Number mRNA
NM_005318
Chromosomal Location
22q13.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome
Molecular Weight
20.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
H1-0
Species
Human
Protein ID
NP_005309
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3005
Uniprot URL
https://www.uniprot.org/uniprot/P07305
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005318
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005309
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