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BTBD7 (NM_018167) Human Recombinant Protein

Product Specifications

Background

Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity) .[UniProtKB/Swiss-Prot Function]

Synonyms

FUP1

Gene ID

55727

UniProt

Q9P203

Accession Number mRNA

NM_018167

Chromosomal Location

14q32.12

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Molecular Weight

45.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BTBD7

Species

Human

Protein ID

NP_060637

Overview

Purified recombinant protein of Human BTB (POZ) domain containing 7 (BTBD7), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55727

Uniprot URL

https://www.uniprot.org/uniprot/Q9P203

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018167

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060637

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