Retinoic Acid Receptor alpha (RARA) (NM_000964) Human Recombinant Protein
Selected Variant
PH30888E6
Size: 50 µg
Product Specifications
Background
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
Overview
Purified recombinant protein of Human retinoic acid receptor, alpha (RARA), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
NR1B1; RAR
Gene ID
5914
UniProt
P10276, Q6I9R7
Accession Number mRNA
NM_000964
Chromosomal Location
17q21.2
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Acute myeloid leukemia, Pathways in cancer
Field of Research
Acute myeloid leukemia, Pathways in cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Molecular Weight
78.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RARA
Species
Human
Protein ID
NP_000955
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5914
Uniprot URL
https://www.uniprot.org/uniprot/P10276
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000964
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000955
Price
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