DUSP26 (NM_024025) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Synonyms
DSP-4; DUSP24; LDP-4; LDP4; MKP-8; MKP8; NATA1; NEAP; SKRP3
Gene ID
78986
UniProt
Q9BV47
Accession Number mRNA
NM_024025
Chromosomal Location
8p12
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome, Phosphatase
Molecular Weight
51.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DUSP26
Species
Human
Protein ID
NP_076930
Overview
Purified recombinant protein of Human dual specificity phosphatase 26 (putative) (DUSP26), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/78986
Uniprot URL
https://www.uniprot.org/uniprot/Q9BV47
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024025
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076930
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