GCAP3 (GUCA1C) (NM_005459) Human Recombinant Protein
Product Specifications
Background
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca (2+) -sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human guanylate cyclase activator 1C (GUCA1C), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
GCAP3
Gene ID
9626
UniProt
O95843
Accession Number mRNA
NM_005459
Chromosomal Location
3q13.13
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Olfactory transduction
Field of Research
Olfactory transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Molecular Weight
51.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GUCA1C
Species
Human
Protein ID
NP_005450
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9626
Uniprot URL
https://www.uniprot.org/uniprot/O95843
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005459
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005450
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