C1orf146 (NM_001012425) Human Recombinant Protein

Product Specifications

Background

Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (By similarity) . Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (By similarity) . Required for the localization of TEX11 and MSH4 to recombination intermediates (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human chromosome 1 open reading frame 146 (C1orf146), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

SCRE; SPO16

Gene ID

388649

UniProt

Q5VVC0

Accession Number mRNA

NM_001012425

Chromosomal Location

1p22.1

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Molecular Weight

48.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.