C1orf146 (NM_001012425) Human Recombinant Protein
Product Specifications
Background
Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (By similarity) . Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (By similarity) . Required for the localization of TEX11 and MSH4 to recombination intermediates (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human chromosome 1 open reading frame 146 (C1orf146), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
SCRE; SPO16
Gene ID
388649
UniProt
Q5VVC0
Accession Number mRNA
NM_001012425
Chromosomal Location
1p22.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Molecular Weight
48.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C1orf146
Species
Human
Protein ID
NP_001012425
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/388649
Uniprot URL
https://www.uniprot.org/uniprot/Q5VVC0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001012425
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001012425
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