CDC42SE2 (NM_020240) Human Recombinant Protein
Product Specifications
Background
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.[UniProtKB/Swiss-Prot Function]
Synonyms
SPEC2
Gene ID
56990
UniProt
Q9NRR3
Accession Number mRNA
NM_020240
Chromosomal Location
5q31.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome
Molecular Weight
37 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CDC42SE2
Species
Human
Protein ID
NP_064625
Overview
Purified recombinant protein of Human CDC42 small effector 2 (CDC42SE2), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56990
Uniprot URL
https://www.uniprot.org/uniprot/Q9NRR3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020240
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_064625
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