SNRPB (NM_003091) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB1
Gene ID
6628
UniProt
P14678, Q66K91
Accession Number mRNA
NM_003091
Chromosomal Location
20p13
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Spliceosome, Systemic lupus erythematosus
Field of Research
Spliceosome, Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Stem cell - Pluripotency
Molecular Weight
51.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SNRPB
Species
Human
Protein ID
NP_003082
Overview
Purified recombinant protein of Human small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6628
Uniprot URL
https://www.uniprot.org/uniprot/P14678
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003091
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003082
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