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NPPC (NM_024409) Human Recombinant Protein

Product Specifications

Background

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]

Overview

Purified recombinant protein of Human natriuretic peptide C (NPPC), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

CNP; CNP2

Gene ID

4880

UniProt

P23582, E5LCN7

Accession Number mRNA

NM_024409

Chromosomal Location

2q37.1

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Function

Secreted Protein

Molecular Weight

41.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NPPC

Species

Human

Protein ID

NP_077720

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4880

Uniprot URL

https://www.uniprot.org/uniprot/P23582

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_024409

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_077720

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