GTSE1 (NM_016426) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
Synonyms
B99
Gene ID
51512
UniProt
Q9NYZ3
Accession Number mRNA
NM_016426
Chromosomal Location
22q13.31
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
P53 signaling pathway
Field of Research
P53 signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome
Molecular Weight
106.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GTSE1
Species
Human
Protein ID
NP_057510
Overview
Purified recombinant protein of Human G-2 and S-phase expressed 1 (GTSE1), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51512
Uniprot URL
https://www.uniprot.org/uniprot/Q9NYZ3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016426
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057510
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