GTSE1 (NM_016426) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human G-2 and S-phase expressed 1 (GTSE1), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

B99

Gene ID

51512

UniProt

Q9NYZ3

Accession Number mRNA

NM_016426

Chromosomal Location

22q13.31

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

P53 signaling pathway

Field of Research

P53 signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Function

Druggable Genome

Molecular Weight

106.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.