NDUFA11 (NM_175614) Human Recombinant Protein
Product Specifications
Background
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Overview
Purified recombinant protein of Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa (NDUFA11), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
B14.7; CI-B14.7; MC1DN14
Gene ID
126328
UniProt
Q86Y39
Accession Number mRNA
NM_175614
Chromosomal Location
19p13.3
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Metabolic pathways, Oxidative phosphorylation
Field of Research
Metabolic pathways, Oxidative phosphorylation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Transmembrane
Molecular Weight
42.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NDUFA11
Species
Human
Protein ID
NP_783313
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/126328
Uniprot URL
https://www.uniprot.org/uniprot/Q86Y39
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_175614
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_783313
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