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HAND1 (NM_004821) Human Recombinant Protein

Selected Variant

PH30785E1

Size: 50 µg

Product Specifications

Background

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human heart and neural crest derivatives expressed 1 (HAND1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

BHLHa27; eHand; Hxt; Thing1

Gene ID

9421

UniProt

O96004

Accession Number mRNA

NM_004821

Chromosomal Location

5q33.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

Molecular Weight

23.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HAND1

Species

Human

Protein ID

NP_004812

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9421

Uniprot URL

https://www.uniprot.org/uniprot/O96004

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004821

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004812

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