HAND1 (NM_004821) Human Recombinant Protein
Selected Variant
PH30785E1
Size: 50 µg
Product Specifications
Background
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human heart and neural crest derivatives expressed 1 (HAND1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
BHLHa27; eHand; Hxt; Thing1
Gene ID
9421
UniProt
O96004
Accession Number mRNA
NM_004821
Chromosomal Location
5q33.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Molecular Weight
23.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HAND1
Species
Human
Protein ID
NP_004812
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9421
Uniprot URL
https://www.uniprot.org/uniprot/O96004
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004821
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004812
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