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GNAT1 (NM_000172) Human Recombinant Protein

Product Specifications

Background

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]

Synonyms

CSNB1G; CSNBAD3; GBT1; GNATR

Gene ID

2779

UniProt

P11488, A1LQ23

Accession Number mRNA

NM_000172

Chromosomal Location

3p21.31

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome

Molecular Weight

39.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GNAT1

Species

Human

Protein ID

NP_000163

Overview

Purified recombinant protein of Human guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 2, full length, with N-terminal His tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2779

Uniprot URL

https://www.uniprot.org/uniprot/P11488

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000172

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000163

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