GNAT1 (NM_000172) Human Recombinant Protein
Product Specifications
Background
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]
Synonyms
CSNB1G; CSNBAD3; GBT1; GNATR
Gene ID
2779
UniProt
P11488, A1LQ23
Accession Number mRNA
NM_000172
Chromosomal Location
3p21.31
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome
Molecular Weight
39.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNAT1
Species
Human
Protein ID
NP_000163
Overview
Purified recombinant protein of Human guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 2, full length, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2779
Uniprot URL
https://www.uniprot.org/uniprot/P11488
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000172
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000163
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items