PPIL5 (LRR1) (NM_203467) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene contains a leucine-rich repeat (LRR) . It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Overview
Purified recombinant protein of Human leucine rich repeat protein 1 (LRR1), transcript variant 3, full length, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
4-1BBLRR; LRR-1; PPIL5
Gene ID
122769
UniProt
Q96L50, A0A384MTQ0, Q6AWA7
Accession Number mRNA
NM_203467
Chromosomal Location
14q21.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome
Molecular Weight
16.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LRR1
Species
Human
Protein ID
NP_982292
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/122769
Uniprot URL
https://www.uniprot.org/uniprot/Q96L50
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_203467
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_982292
Frequently Asked Questions
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