FLCN (NM_144606) Human Recombinant Protein
Product Specifications
Background
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
BHD; DENND8B; FLCL
Gene ID
201163
UniProt
Q8NFG4, A0A0S2Z5Y7
Accession Number mRNA
NM_144606
Chromosomal Location
17p11.2
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Renal cell carcinoma
Field of Research
Renal cell carcinoma
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Druggable Genome
Molecular Weight
65.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FLCN
Species
Human
Protein ID
NP_653207
Overview
Purified recombinant protein of Human folliculin (FLCN), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/201163
Uniprot URL
https://www.uniprot.org/uniprot/Q8NFG4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144606
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_653207
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