FLCN (NM_144606) Human Recombinant Protein

Product Specifications

Background

This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human folliculin (FLCN), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

BHD; DENND8B; FLCL

Gene ID

201163

UniProt

Q8NFG4, A0A0S2Z5Y7

Accession Number mRNA

NM_144606

Chromosomal Location

17p11.2

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

Renal cell carcinoma

Field of Research

Renal cell carcinoma

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome

Molecular Weight

65.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.