Pericentrin 1 (NUP85) (NM_024844) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms
FROUNT; NPHS17; Nup75
Gene ID
79902
UniProt
Q9BW27
Accession Number mRNA
NM_024844
Chromosomal Location
17q25.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Molecular Weight
102.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NUP85
Species
Human
Protein ID
NP_079120
Overview
Purified recombinant protein of Human nucleoporin 85kDa (NUP85), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79902
Uniprot URL
https://www.uniprot.org/uniprot/Q9BW27
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024844
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079120
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