Pericentrin 1 (NUP85) (NM_024844) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Overview

Purified recombinant protein of Human nucleoporin 85kDa (NUP85), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

FROUNT; NPHS17; Nup75

Gene ID

79902

UniProt

Q9BW27

Accession Number mRNA

NM_024844

Chromosomal Location

17q25.1

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Molecular Weight

102.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.