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FGF13 (NM_004114) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]

Synonyms

DEE90; FGF-13; FGF2; FHF-2; FHF2; LINC00889

Gene ID

2258

UniProt

Q92913, A8K1P5

Accession Number mRNA

NM_004114

Chromosomal Location

Xq26.3-q27.1

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Field of Research

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Secreted Protein

Molecular Weight

55.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGF13

Species

Human

Protein ID

NP_004105

Overview

Purified recombinant protein of Human fibroblast growth factor 13 (FGF13), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2258

Uniprot URL

https://www.uniprot.org/uniprot/Q92913

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004114

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004105

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