KDM4D (NM_018039) Human Recombinant Protein
Product Specifications
Background
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human lysine (K) -specific demethylase 4D (KDM4D), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
JMJD2D
Gene ID
55693
UniProt
Q6B0I6
Accession Number mRNA
NM_018039
Chromosomal Location
11q21
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Molecular Weight
86.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KDM4D
Species
Human
Protein ID
NP_060509
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55693
Uniprot URL
https://www.uniprot.org/uniprot/Q6B0I6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018039
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060509
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