Nkx6.1 (NKX6-1) (NM_006168) Human Recombinant Protein
Product Specifications
Background
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]
Overview
Purified recombinant protein of Human NK6 homeobox 1 (NKX6-1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
NKX6.1; NKX6A
Gene ID
4825
UniProt
P78426
Accession Number mRNA
NM_006168
Chromosomal Location
4q21.23
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Maturity onset diabetes of the young
Field of Research
Maturity onset diabetes of the young
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Transcription Factors
Molecular Weight
65.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NKX6-1
Species
Human
Protein ID
NP_006159
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4825
Uniprot URL
https://www.uniprot.org/uniprot/P78426
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006168
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006159
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