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NOL5A (NOP56) (NM_006392) Human Recombinant Protein

Product Specifications

Background

Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016]

Overview

Purified recombinant protein of Human NOP56 ribonucleoprotein homolog (yeast) (NOP56), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

NOL5A; SCA36

Gene ID

10528

UniProt

O00567

Accession Number mRNA

NM_006392

Chromosomal Location

20p13

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Stem cell - Pluripotency

Molecular Weight

93.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NOP56

Species

Human

Protein ID

NP_006383

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10528

Uniprot URL

https://www.uniprot.org/uniprot/O00567

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006392

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006383

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