NOL5A (NOP56) (NM_006392) Human Recombinant Protein
Product Specifications
Background
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016]
Overview
Purified recombinant protein of Human NOP56 ribonucleoprotein homolog (yeast) (NOP56), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
NOL5A; SCA36
Gene ID
10528
UniProt
O00567
Accession Number mRNA
NM_006392
Chromosomal Location
20p13
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Stem cell - Pluripotency
Molecular Weight
93.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NOP56
Species
Human
Protein ID
NP_006383
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10528
Uniprot URL
https://www.uniprot.org/uniprot/O00567
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006392
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006383
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