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Caveolin 2 (CAV2) (NM_198212) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462) . [provided by RefSeq, May 2011]

Overview

Purified recombinant protein of Human caveolin 2 (CAV2), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

CAV

Gene ID

858

UniProt

P51636

Accession Number mRNA

NM_198212

Chromosomal Location

7q31.2

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

Focal adhesion

Field of Research

Focal adhesion

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome, Transmembrane

Molecular Weight

40.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CAV2

Species

Human

Protein ID

NP_937855

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/858

Uniprot URL

https://www.uniprot.org/uniprot/P51636

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_198212

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_937855

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