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ZIC1 (NM_003412) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human Zic family member 1 (ZIC1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

BAIDCS; CRS6; ZIC; ZNF201

Gene ID

7545

UniProt

Q15915

Accession Number mRNA

NM_003412

Chromosomal Location

3q24

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Druggable Genome

Molecular Weight

76.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ZIC1

Species

Human

Protein ID

NP_003403

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7545

Uniprot URL

https://www.uniprot.org/uniprot/Q15915

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003412

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003403

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