CD89 (FCAR) (NM_133269) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CD89; CTB-61M7.2; FcalphaRI
Gene ID
2204
UniProt
P24071, A0A024R4N4, Q92588
Accession Number mRNA
NM_133269
Chromosomal Location
19q13.42
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea.
Function
Transmembrane
Molecular Weight
55.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FCAR
Species
Human
Protein ID
NP_579803
Overview
Purified recombinant protein of Human Fc fragment of IgA, receptor for (FCAR), transcript variant 2, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2204
Uniprot URL
https://www.uniprot.org/uniprot/P24071
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133269
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_579803
Curated Selection
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