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CD89 (FCAR) (NM_133269) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human Fc fragment of IgA, receptor for (FCAR), transcript variant 2, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

CD89; CTB-61M7.2; FcalphaRI

Gene ID

2204

UniProt

P24071, A0A024R4N4, Q92588

Accession Number mRNA

NM_133269

Chromosomal Location

19q13.42

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea.

Function

Transmembrane

Molecular Weight

55.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FCAR

Species

Human

Protein ID

NP_579803

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2204

Uniprot URL

https://www.uniprot.org/uniprot/P24071

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_133269

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_579803

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