Cripto1 (TDGF1) (NM_003212) Human Recombinant Protein
Product Specifications
Background
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Synonyms
CR; CR-1; CRGF; CRIPTO
Gene ID
6997
UniProt
P13385
Accession Number mRNA
NM_003212
Chromosomal Location
3p21.31
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl
Function
Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Molecular Weight
45.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TDGF1
Species
Human
Protein ID
NP_003203
Overview
Purified recombinant protein of Human teratocarcinoma-derived growth factor 1 (TDGF1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6997
Uniprot URL
https://www.uniprot.org/uniprot/P13385
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003212
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003203
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