VDAC2 (NM_003375) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Synonyms
POR
Gene ID
7417
UniProt
P45880, A0A024QZT0
Accession Number mRNA
NM_003375
Chromosomal Location
10q22.2
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Calcium signaling pathway, Huntington's disease, Parkinson's disease
Field of Research
Calcium signaling pathway, Huntington's disease, Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl
Function
Druggable Genome, Ion Channels: Other
Molecular Weight
59.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VDAC2
Species
Human
Protein ID
NP_003366
Overview
Purified recombinant protein of Human voltage-dependent anion channel 2 (VDAC2), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7417
Uniprot URL
https://www.uniprot.org/uniprot/P45880
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003375
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003366
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal ATP2C2 Antibody [DyLight 650]](https://cdn.genprice.uk/genprice/genprice2.png)
