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USP36 (NM_025090) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016]

Overview

Purified recombinant protein of Human ubiquitin specific peptidase 36 (USP36), transcript variant 2, Gln589-Asp972, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

DUB1

Gene ID

57602

UniProt

Q9P275

Accession Number mRNA

NM_025090

Chromosomal Location

17q25.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol

Function

Druggable Genome, Protease

Molecular Weight

41.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

USP36

Species

Human

Protein ID

NP_079366

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57602

Uniprot URL

https://www.uniprot.org/uniprot/Q9P275

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_025090

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_079366

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