USP36 (NM_025090) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016]
Synonyms
DUB1
Gene ID
57602
UniProt
Q9P275
Accession Number mRNA
NM_025090
Chromosomal Location
17q25.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
41.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
USP36
Species
Human
Protein ID
NP_079366
Overview
Purified recombinant protein of Human ubiquitin specific peptidase 36 (USP36), transcript variant 2, Gln589-Asp972, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57602
Uniprot URL
https://www.uniprot.org/uniprot/Q9P275
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025090
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079366
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