SLC30A4 (NM_013309) Human Recombinant Protein
Product Specifications
Background
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450) . SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]) .[supplied by OMIM, Mar 2008]
Synonyms
ZnT-4; ZNT4
Gene ID
7782
UniProt
O14863
Accession Number mRNA
NM_013309
Chromosomal Location
15q21.1
Expression System
E. coli
Tag
N-His-ABP
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol
Function
Transmembrane
Molecular Weight
25.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SLC30A4
Species
Human
Protein ID
NP_037441
Overview
Purified recombinant protein of Human solute carrier family 30 (zinc transporter), member 4 (SLC30A4), Pro336-Gln425, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7782
Uniprot URL
https://www.uniprot.org/uniprot/O14863
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013309
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037441
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