ABHD4 (NM_022060) Human Recombinant Protein
Product Specifications
Background
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE) . Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human abhydrolase domain containing 4 (ABHD4), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
ABH4
Gene ID
63874
UniProt
Q8TB40
Accession Number mRNA
NM_022060
Chromosomal Location
14q11.2
Expression System
E. coli
Tag
N-GST, C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1%Sarkosyl
Function
Protease
Molecular Weight
66.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ABHD4
Species
Human
Protein ID
NP_071343
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/63874
Uniprot URL
https://www.uniprot.org/uniprot/Q8TB40
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022060
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_071343
Curated Selection
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