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Small EDRK rich factor 1 (SERF1B) (NM_022978) Human Recombinant Protein

Product Specifications

Background

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is the centromeric copy which is identical to the telomeric copy. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. The gene encodes a protein of unknown function which bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. [provided by RefSeq, Jul 2008]

Synonyms

FAM2B; h4F5; H4F5C

Gene ID

728492

UniProt

O75920

Accession Number mRNA

NM_022978

Chromosomal Location

5q13.2

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Transmembrane

Molecular Weight

40.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SERF1B

Species

Human

Protein ID

NP_075267

Overview

Purified recombinant protein of Human small EDRK-rich factor 1B (centromeric) (SERF1B), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/728492

Uniprot URL

https://www.uniprot.org/uniprot/O75920

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_022978

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_075267

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