RSPO2 (NM_178565) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Purified recombinant protein of Human R-spondin 2 homolog (Xenopus laevis) (RSPO2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
CRISTIN2; HHRRD; TETAMS2
Gene ID
340419
UniProt
Q6UXX9, B3KVP3
Accession Number mRNA
NM_178565
Chromosomal Location
8q23.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Secreted Protein
Molecular Weight
56.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RSPO2
Species
Human
Protein ID
NP_848660
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/340419
Uniprot URL
https://www.uniprot.org/uniprot/Q6UXX9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178565
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_848660
Frequently Asked Questions
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