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RSPO2 (NM_178565) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Overview

Purified recombinant protein of Human R-spondin 2 homolog (Xenopus laevis) (RSPO2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

CRISTIN2; HHRRD; TETAMS2

Gene ID

340419

UniProt

Q6UXX9, B3KVP3

Accession Number mRNA

NM_178565

Chromosomal Location

8q23.1

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Secreted Protein

Molecular Weight

56.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RSPO2

Species

Human

Protein ID

NP_848660

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/340419

Uniprot URL

https://www.uniprot.org/uniprot/Q6UXX9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_178565

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_848660

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