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APOBEC1 (NM_001644) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP) . This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]

Overview

Purified recombinant protein of Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (APOBEC1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

APOBEC-1; BEDP; CDAR1; HEPR

Gene ID

339

UniProt

P41238

Accession Number mRNA

NM_001644

Chromosomal Location

12p13.31

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Molecular Weight

56 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

APOBEC1

Species

Human

Protein ID

NP_001635

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/339

Uniprot URL

https://www.uniprot.org/uniprot/P41238

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001644

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001635

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