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HS2ST1 (NM_012262) Human Recombinant Protein

Product Specifications

Background

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]

Synonyms

DJ604K5.2; NFSRA

Gene ID

9653

UniProt

Q7LGA3

Accession Number mRNA

NM_012262

Chromosomal Location

1p22.3

Expression System

E. coli

Tag

N-His-ABP

Related Pathways

Heparan sulfate biosynthesis

Field of Research

Heparan sulfate biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

Molecular Weight

24.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HS2ST1

Species

Human

Protein ID

NP_036394

Overview

Purified recombinant protein of Human heparan sulfate 2-O-sulfotransferase 1 (HS2ST1), transcript variant 1, Asn29-His106, with N-terminal His-ABP tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9653

Uniprot URL

https://www.uniprot.org/uniprot/Q7LGA3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012262

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036394

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