HS2ST1 (NM_012262) Human Recombinant Protein
Product Specifications
Background
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
Synonyms
DJ604K5.2; NFSRA
Gene ID
9653
UniProt
Q7LGA3
Accession Number mRNA
NM_012262
Chromosomal Location
1p22.3
Expression System
E. coli
Tag
N-His-ABP
Related Pathways
Heparan sulfate biosynthesis
Field of Research
Heparan sulfate biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.
Molecular Weight
24.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HS2ST1
Species
Human
Protein ID
NP_036394
Overview
Purified recombinant protein of Human heparan sulfate 2-O-sulfotransferase 1 (HS2ST1), transcript variant 1, Asn29-His106, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9653
Uniprot URL
https://www.uniprot.org/uniprot/Q7LGA3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012262
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036394
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