VPS35 (NM_018206) Human Recombinant Protein
Product Specifications
Background
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]
Synonyms
MEM3; PARK17
Gene ID
55737
UniProt
Q96QK1
Accession Number mRNA
NM_018206
Chromosomal Location
16q11.2
Expression System
E. coli
Tag
N-His-ABP
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.
Molecular Weight
28.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VPS35
Species
Human
Protein ID
NP_060676
Overview
Purified recombinant protein of Human vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35), Ser437-Asp551, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55737
Uniprot URL
https://www.uniprot.org/uniprot/Q96QK1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018206
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060676
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