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VPS35 (NM_018206) Human Recombinant Protein

Product Specifications

Background

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35), Ser437-Asp551, with N-terminal His-ABP tag, expressed in E. coli, 50ug

Synonyms

MEM3; PARK17

Gene ID

55737

UniProt

Q96QK1

Accession Number mRNA

NM_018206

Chromosomal Location

16q11.2

Expression System

E. coli

Tag

N-His-ABP

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

Molecular Weight

28.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

VPS35

Species

Human

Protein ID

NP_060676

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55737

Uniprot URL

https://www.uniprot.org/uniprot/Q96QK1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018206

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060676

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