ZNF521 (NM_015461) Human Recombinant Protein
Selected Variant
PH30452E1
Size: 50 µg
Product Specifications
Background
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human zinc finger protein 521 (ZNF521), Lys1077-Glu1150, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Synonyms
EHZF; Evi3
Gene ID
25925
UniProt
Q96K83
Accession Number mRNA
NM_015461
Chromosomal Location
18q11.2
Expression System
E. coli
Tag
N-His-ABP
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.
Molecular Weight
22.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ZNF521
Species
Human
Protein ID
NP_056276
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25925
Uniprot URL
https://www.uniprot.org/uniprot/Q96K83
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015461
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056276
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