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FGFBP1 (NM_005130) Human Recombinant Protein

Product Specifications

Background

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

Overview

Purified recombinant protein of Human fibroblast growth factor binding protein 1 (FGFBP1), Lys24-Cys234, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17

Gene ID

9982

UniProt

Q14512

Accession Number mRNA

NM_005130

Chromosomal Location

4p15.32

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Secreted Protein

Molecular Weight

23.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGFBP1

Species

Human

Protein ID

NP_005121

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9982

Uniprot URL

https://www.uniprot.org/uniprot/Q14512

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005130

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005121

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