FGFBP1 (NM_005130) Human Recombinant Protein
Product Specifications
Background
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
Overview
Purified recombinant protein of Human fibroblast growth factor binding protein 1 (FGFBP1), Lys24-Cys234, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17
Gene ID
9982
UniProt
Q14512
Accession Number mRNA
NM_005130
Chromosomal Location
4p15.32
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Secreted Protein
Molecular Weight
23.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FGFBP1
Species
Human
Protein ID
NP_005121
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9982
Uniprot URL
https://www.uniprot.org/uniprot/Q14512
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005130
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005121
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