ULK2 (NM_014683) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]
Synonyms
ATG1B; Unc51.2
Gene ID
9706
UniProt
Q8IYT8
Accession Number mRNA
NM_014683
Chromosomal Location
17p11.2
Expression System
E. coli
Tag
N-His
Related Pathways
MTOR signaling pathway, Regulation of autophagy
Field of Research
MTOR signaling pathway, Regulation of autophagy
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Protein Kinase
Molecular Weight
31.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ULK2
Species
Human
Protein ID
NP_055498
Overview
Purified recombinant protein of Human unc-51-like kinase 2 (C. elegans) (ULK2), transcript variant 1, Arg408-Pro702, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9706
Uniprot URL
https://www.uniprot.org/uniprot/Q8IYT8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014683
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055498
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