ULK2 (NM_014683) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]

Overview

Purified recombinant protein of Human unc-51-like kinase 2 (C. elegans) (ULK2), transcript variant 1, Arg408-Pro702, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

ATG1B; Unc51.2

Gene ID

9706

UniProt

Q8IYT8

Accession Number mRNA

NM_014683

Chromosomal Location

17p11.2

Expression System

E. coli

Tag

N-His

Related Pathways

MTOR signaling pathway, Regulation of autophagy

Field of Research

MTOR signaling pathway, Regulation of autophagy

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Protein Kinase

Molecular Weight

31.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.