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Inhibin alpha (INHA) (NM_002191) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]

Overview

Purified recombinant protein of Human inhibin, alpha (INHA), Ser233-Ile366, with N-terminal His-Trx tag, expressed in E. coli, 50ug

Synonyms

A-inhibin subunit; inhibin, alpha; inhibin alpha subunit

Gene ID

3623

UniProt

P05111

Accession Number mRNA

NM_002191

Chromosomal Location

2q35

Expression System

E. coli

Tag

N-His-Trx

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Secreted Protein

Molecular Weight

35.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

INHA

Species

Human

Protein ID

NP_002182

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3623

Uniprot URL

https://www.uniprot.org/uniprot/P05111

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002191

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002182

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