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USP48 (NM_032236) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human ubiquitin specific peptidase 48 (USP48), transcript variant 1, Pro361-Tyr743, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

RAP1GA1; USP31

Gene ID

84196

UniProt

Q86UV5

Accession Number mRNA

NM_032236

Chromosomal Location

1p36.12

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Protease, Transmembrane

Molecular Weight

44.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

USP48

Species

Human

Protein ID

NP_115612

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/84196

Uniprot URL

https://www.uniprot.org/uniprot/Q86UV5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_032236

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_115612

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