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LNX1 (NM_032622) Human Recombinant Protein

Product Specifications

Background

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human ligand of numb-protein X 1 (LNX1), transcript variant 2, Met260-Val528, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

LNX; MPDZ; PDZRN2

Gene ID

84708

UniProt

Q8TBB1

Accession Number mRNA

NM_032622

Chromosomal Location

4q12

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome

Molecular Weight

29.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LNX1

Species

Human

Protein ID

NP_116011

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/84708

Uniprot URL

https://www.uniprot.org/uniprot/Q8TBB1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_032622

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_116011

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