LNX1 (NM_032622) Human Recombinant Protein
Product Specifications
Background
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
LNX; MPDZ; PDZRN2
Gene ID
84708
UniProt
Q8TBB1
Accession Number mRNA
NM_032622
Chromosomal Location
4q12
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome
Molecular Weight
29.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LNX1
Species
Human
Protein ID
NP_116011
Overview
Purified recombinant protein of Human ligand of numb-protein X 1 (LNX1), transcript variant 2, Met260-Val528, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84708
Uniprot URL
https://www.uniprot.org/uniprot/Q8TBB1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032622
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_116011
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